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KMID : 1123920060200010193
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Korean Journal of Oriental Physiology and Pathology
2006 Volume.20 No. 1 p.193 ~ p.195
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Antifungal Activity of Ethanol Extract from Lepidolaena clavigera on the Dermatophytic Fungus
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Lee Jae-Sook
Yu Byung-Soo
Baek Seung-Hwa
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Abstract
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The effects of ethanol extract from Lepidolaena clavigera (L. clavigera) on antifungal activity were investigated. The crude ethanol extract of L. clavigera inhibited the growth of the Gram positive bacterium Bacillus subtilis ATCC 19659, (1 mm inhibition zone at 150 ) and the dermatophytic fungus Trichophyon mentagrophyes ATCC 28185, (2 mm inhibition zone at 150 ), and cytotoxic to P388 murine leukaemia cells ATCC CCL 46 P388D1, (IC50 >12,500 ) and cytotoxic to BSC monkey kidney cells (@ 5 mg/mL, 150 ; ++: 50% activity). We suppose that this crude ethanol extract of L. clavigera is the antifungal activity.
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KEYWORD
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Lepidolaena clavigera, Bacillus subtilis, Trichophyton mentagrophyes, antifungal activity
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